Cirrhosis Writhes and Moves On

Sir Rosis rose and razed his host
who resignedly retried
to raise a glass as in times past.
The glass broke and he sighed.
‘Do you recall?’ Sir Rosis asked,
‘the hogsheads and the casks
you lavished on your liver giving
it a keg of tasks?’
His host’s mind had been binged so much
that its memories were mired
in alcohol. The host drew a blank
and looked puzzled when it fired.
‘Your brain is mixing metaphors!’
Sir Rosis said and fled
to seek out other likely lads
with livers less stone dead.

Verbal-Rorschach Prescriptions

What I write, the words, and their images and rhythms,
serve as records of ‘me as subject’ — my perceptions
that a psychologist can analyse, as can algorithms,
to examine the feints and parries and deceptions
in my verse and worse to show personality
and emotional functioning if any. There I go.
With a Rorschach here, and a decision tree over there
they’re no limits to what psychology claims to show.

Wide-Awake Pedant

‘It cannot be true,’ he says – and he hopes that is true –
‘that I’ve lain awake half the night, and I’ve sleepwalked the other.’
‘Half,’ he adds pedantically, as true pedants do.
He misses the blanket he’d discarded in fear it would smother
his soul if he slept. He watches his fingers turn blue
with his red eyes shut tight, if that’s possible, and he implores
the god Morpheus to aid him in becoming a mammal that snores.

Vive le HSF-1! Vive le DAF-16!

Do not forget that janitors grow old.
They sweep up and they keep on sweeping up
on automatic, no need to be told.
They sweep until they age and pass the cup

to no one. Without replacements you forget.
Commemorative plaques give way to Plaque
Forgetful, and it is not over yet.
First memory, then muscles — the attack

moves on until the person who was you
subsides into a shadow form that leaves
but little more than molecules and glue
of the who it was your faithful lover grieves.

No one can stop the hell there is to pay
when janitors grow old, retire, can’t play.

 
————–
Hooray, they’ve found the key to keep our minds
preserved from dying at Alzheimer’s hands:
They’ve identified the janitorial kinds
of cells we share with worm C. elegans.

The scientists are cautious, but the press
exults as if they’ve found the holy grail.
A little worm shall lead us, they profess,
and if it does not, others in the pail

will serve to break Death’s hold on human brains.
With memories intact we shall not die!
The ONLY standing hurdle that remains
will fall, now we’ve the key with which to pry

our freedom from Alzheimer’s mortal clock.
Now ALL that’s left to do is find the lock.

The inspiration for this pair of sonnets was an AP article “Cleanup Crew Clears Way for Research. Scientists have discovered molecular janitors [one of these proteins is named HSF-1, and another is called DAF-16] that clear away a sticky protein that plays a role in Alzheimer’s disease until they get old and quit sweeping up. The finding helps explain why Alzheimer’s is a disease of aging. More importantly, it suggests a potential new weapon: drugs that give nature’s cleanup crews a boost….”

Morpheus Himself is Restive

It’s 3 AM. The therapy: hold a book
that I can read but won’t if I turn on the light
is working, is that therapy, although it took
at 2:45 all of my will and might
to keep the room too dark to read or write.
I ride loose thoughts that float to where it’s day,
to Tokyo, Seoul, Rangoon, Bombay:
so many places and people, a gazillion flies.
It’s 3:45. Morpheus tells me it’s okay,
and that he can’t sleep no matter what he tries.